Young Investigators Award Program

Previous Award Winners

2010 Winners | 2009 Winners | 2008 Winners | 2007 Winners | 2006 Winners

2010 Winners

ENTELLIGENCE 2010 Award Winners Press Release

Eric Douglas Austin, MD, MSCI
Assistant Professor
Department of Pediatrics
Vanderbilt University Medical Center
Project Title: Sex Hormone Abnormalities in Pulmonary Arterial Hypertension

Abstract

Angela V. Ghatnekar, PhD
Post-Doctoral Scholar
Department of Rheumatology
Medical University of South Carolina
Project Title: The Role of GATA-6 in Pulmonary Arterial Hypertension

Abstract

Jason Gien, MD
Assistant Professor Pediatrics
Department of Pediatrics
University of Colorado Health Sciences Center
Project Title: ET-1-Rho-kinase Interactions in the Pathogenesis of Neonatal Pulmonary Hypertension

Abstract

Michael J. Passineau, PhD
Assistant Professor
Department of Medicine/Cardiovascular
Allegheny General Hospital
Project Title: Gene Therapy to Drive Endogenous Biosynthesis of Prostacyclin

Abstract

Michael York, MD
Assistant Professor of Medicine
Department of Medicine/Arthritis
Boston University Medical Center
Project Title: dsRNA Stimulates Toll-like Receptor-3 and Increases Endothelin-1 Production by Pulmonary Artery Endothelial Cells

Abstract

2009 Winners

ENTELLIGENCE 2009 Award Winners Press Release

Daniel J. Kass, MD
Assistant Professor of Medicine
Division of Pulmonary, Allergy, and Critical Care Medicine
Columbia University
College of Physicians and Surgeons
New York, New York
Project Title: Targeting the MetAP2 Pathway in Pulmonary Arterial Hypertension

Abstract

Sean E. McLean, MD
Assistant Professor of Surgery
Division of Pediatric Surgery
UNC School of Medicine
Chapel Hill, North Carolina
Project Title: Smooth Muscle Cell Related Vascular Remodeling in Pulmonary Hypertension in Congenital Diaphragmatic Hernia

Abstract

Alexander R. Opotowsky, MD, MPH
Senior Fellow
Adult Congenital Heart Disease and Pulmonary Hypertension
Department of Cardiology
Children’s Hospital Boston
Boston Adult Congenital Heart Program
Boston, Massachusetts
Project Title: The Epidemiolgy and Determinants of Hospitalization for Pulmonary Hypertension in the United States

Abstract

Michael Eric Yeager, PhD
Instructor of Pediatrics
Department of Pediatrics
Section of Cardiology
University of Colorado School of Medicine
Aurora, Colorado
Project Title: Circulating Mesenchymal Precursors in Severe PAH and the Role of Endothelin-1 in their Recruitment and Differentiation into Fibrocytes

Abstract

2008 Winners

Gaurav Choudhary, MD
Staff Cardiologist, Providence VAMC
Assistant Professor of Medicine
Alpert Medical School at Brown University
Project Title: Role of
Endothelin-induced PKC delta activation
in Right Ventricular Hypertrophy
Abstract | Research Page

Hyung J Chun, MD
Fellow in Cardiovascular Medicine
Division of Cardiovascular Medicine
Stanford University School of Medicine
Project Title: Role of the Apelin-APJ Pathway
in Endothelin-1 Signaling and
Pulmonary Arterial Hypertension

Scott D. Halpern, MD, PhD
Assistant Professor of Medicine
Division of Pulmonary, Allergy and Critical Care Medicine
Senior Fellow, Center for Bioethics
University Pennsylvania School of Medicine
Project Title: Racial Differences in Responsiveness
to Endothelin Receptor Antagonists
in Pulmonary Arterial Hypertension

Sayyed A Hamidi, MD
Research Assistant Professor of Medicine
Department of Medicine
Pulmonary/Critical Care Division
State University of New York, Stony Brook
Project Title: A New Combination Therapy for Pulmonary Arterial Hypertension:
Bosentan and VIP
Abstract | Research Page

Sanjiv Shah, MD
Assistant Professor of Medicine
Division of Cardiology, Department of Medicine
Northwestern University Medical Center
Project Title: Genetic Risk Factors for Connective Tissue Disease (CTD)-Associated Pulmonary Arterial Hypertension (PAH)
Research Page

Venkataramana Sidhaye, MD
Assistant Professor
Pulmonary and Critical Care Medicine
Johns Hopkins University
Project Title: Endothelin-1 Mediated Pulmonary
Smooth Muscle Migration is Mediated by AQP1
Abstract | Research Page

Ari Lev Zaiman, MD, PhD
Assistant Professor
Division of Pulmonary Medicine
John Hopkins University
Project Title: Role of Endothelin Abrogration of TGF Signaling in the Vascular Endothelium Attenuates Hypoxia Induced Pulmonary Hypertension

2007 Winners

Yabing Chen, PhD
Assistant Professor
Department of Pathology
UAB School of Medicine
Project Title: PAI-1 Regulates Vascular Remodeling in Hypoxia-Induced Pulmonary Hypertension
Abstract | Research Page

Christopher Fiack, MD
Assistant Clinical Professor
Department of Medicine
John A. Burns School of Medicine
Project Title: Pulmonary Hypertension due to the Left Ventricular Dysfunction

Anna R Hemnes, MD
Clinical Fellow
Department of Medicine, Division of Allergy, Pulmonary Care and Critical Care
Vanderbilt University School of Medicine
Project Title:The Role of Endothelin-1 in Right Ventricular Response to Pressure Overload
Abstract

Jeffrey C Horowitz, MD
Assistant Professor of Medicine
Department of Internal Medicine
Division of Pulmonary and Critical Care Medicine
University of Michigan Health System
Project Title: Regulation of Myofibroblast Resistance to Apoptosis by Endothelin-1
Abstract | Research Page

Meredith A Preuss, PhD
Assistant Professor
Department of Medicine
Division of Human Gene Therapy
UAB School of Medicine
Project Title: Downstream Redox Regulation of Endothelin B Receptor in the Pulmonary Endothelium
Abstract

Olga Rafikova, PhD, MD
Postdoctural Associate
Department of Medicine
University of Pittsburgh
Project Title: Protein Nitration and Inhibition of Cardiac and Vascular Remodeling in Pulmonary Hypertension Endothelin Receptor Antagonists

Megha H. Talati, PhD
Research Instructor in Medicine
Vanderbilt University Medical Center
Project Title: Effect of BMPR2 Mutation in FPAH on ET-1 and ET-1 Receptors and Smad/MAPK Activation by ET-1 Receptors in Lung ECs and PASMCs in the Mouse Model of PAH
Abstract

Yerem Yeghiazarians, MD
Associate Professor of Medicine
Division of Cardiology
University of California, San Francisco
Project Title: Effect of Endothelin Receptor Blockade on Circulating Endothelial
Microparticle Levels in Patients with Pulmonary Hypertension
Abstract | Research Page

2006 Winners

Joel Glasgow, PhD
Assistant Professor
Department of Medicine
Division of Cardiovascular Disease
UAB School of Medicine
Project Title: Gene Delivery for Pulmonary Arterial Hypertension

Zhigang Hong, PhD, MD
Assistant Professor
Department of Medicine
University of Chicago
Project Title: Endothelin-Induced Increase in Pulmonary Vascular
Smooth Muscle Calcium; The Role of Calcium Channels
Abstract

Peter Oishi, MD
Pediatric Clinical Care Specialist
UCSF School of Medicine
Project Title: Endothelin-1 Reactive Oxygen Species Interactions
in Pulmonary Hypertension

Rajni Rao, MD
Assistant Clinical Professor of Medicine
UCSF School of Medicine
Project Title: Quantitative and Qualitative Properties of Endothelial Progenitor Cells in Patients with Pulmonary Hypertension

Giuseppe Valacchi, PhD
Department of Biomedical Sciences
University of Siena
Project Title: Does Tocopherol Homeostasis Play a Role in Endothelin
Mediated Endothelial Dysfunction?
Abstract | Research Page

Roham Zamanian, MD, FCCP
Assistant Professor of Medicine
Director, Adult Pulmonary Hypertension Clinical Service
Division of Pulmonary & Critical Care Medicine
Vera Moulton Wall Center for Pulmonary Vascular Disease
Stanford University School of Medicine
Project Title: The Effect of Endothelin A and B Antagonism on Insulin
Resistance and Outcomes in Patients with Pulmonary Arterial Hypertension
Research Page